I Advice - Health and Fitness

Most people simply don't pay attention to what they eat. They choose food solely on the basis of taste (or worse, packaging). While everyone agrees that food should certainly taste good, there

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

is also a need for our food to be nutritionally sound. If you are not accustomed to evaluating your food choices, grab a package of you favorite food with a nutrition label on it and let's get s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tarted!

When evaluating a nutrition label, pay attention first to the serving size. A particular food, for instance ice cream, may only have 150 calories per serving, but if the serving size is

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

? cup and you eat a whole cup, you have had 300 calories. Paying attention to this one section of the food label alone can help you drastically reduce your caloric intake and help you to lose u

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nwanted pounds.

However, keep in mind that if a food is high in calories per serving it does not mean that you should never eat it. Just reserve those treats for occasional use, making sure tha

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

t eating it does not add up to more calories than you burn that day.

Additionally, all foods can be broken down into three components called macronutrients. These macronutrients are proteins, f

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ats and carbohydrates. There are healthy and not-so-healthy types of each of these macronutrients and they are all listed on food labels. (Micronutrients, which are commonly referred to as vita

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ins and minerals, will not be discussed here, but also can be found on food labels.)

Next pay attention to the fat content of a particular food. You'll likely see listings for total, saturated

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

and trans fats. Although you don't need to stay away from fat altogether (we need some fat in our diets to survive), steer clear of saturated and trans fats as much as possible. Saturated and t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rans fats increase your risk of developing conditions such as diabetes and heart disease. Better fats will be listed as polyunsaturated and monosaturated on food labels. Try getting your daily

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

fat intake from nuts, seeds and plant oils instead of butter, high fat meats and processed snack foods.

Where carbohydrates are concerned, think whole grains instead of processed or refined. On

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

food labels you will see the total amount of carbohydrates listed with the amount of dietary fiber underneath. Foods that are more processed or refined will have less fiber. White bread and pa

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

sta as well as cookies, cakes and candies will be high in processed carbohydrates and low in fiber. Look for items that boast 100% whole grains when shopping for crackers, bread and pasta to red

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

uce your chance of developing diseases such as diabetes, colon cancer and high cholesterol.

Also, be careful of how many calories you drink. Sodas, sports drinks and alcohol contain carbohydrat

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

calories without the benefit of fiber for the most part. These drinks are typically loaded with refined sugar. Stick with water and milk, or 100% juice in limited quantities – no more than 1 g

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

lass a day.

Some meats, and most fruits and vegetables, do not carry nutrition labels. However, a good reference book or web site will list macronutrient values for almost every fruit or vegeta

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ble imaginable. Every day, you need about three to nine grams of protein for every ten pounds of body weight. Most Americans eat more than enough to satisfy this requirement. Make sure your pr

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

otein intake is in balance with what your body requires.

For meals that don't come with a nutrition label, a quick search on the internet will help you find the calorie content of foods from man

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

y different restaurants. Using this information, you can still eat out at your favorite places without overindulging in too many calories.

The key to good health is information. The more you k

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

now, the easier it is to be healthy and fit. Learn about your favorite foods so that you can make good food choices that will enhance your overall health.

By Dr. Jennifer Wetmore copyright 200

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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