I Advice - Health and Fitness

Carbohydrates are one of the basic building blocks of food so they are a very important part of your diet and weig

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ht loss goals. Carbohydrates are in most of the foods that we eat from fruits and vegetables to breads and cereals

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

. Foods that have no or nearly no carbohydrates are meats and oils as well as of course water.

There are two type

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s of carbohydrates and the way that they affect your body is vastly different. One kind of carb, a complex carbohy

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rate such as we find in breads, rice and potatoes takes a long time to break down in your body and can be stored a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s fat fairly easily (like a few pieces of bread). The second kind of carb, the simple carbohydrate is found in fru

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

its and sugar. Simple carbs in low amounts tend to be burned of pretty easily but of course as you take in large a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

mounts of simple carbs (like a chocolate bar).

Now that oyu know about the two kinds of carbs it is important to

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

estrict the amount of carbohydrates in your diet. You will now also notice whether you are more suceptible to eati

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ng those simple or complex carbs. I know that in my house I am the simple carb hoarder and my wife has a weakness

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

for breads, esopecially when we go to the Olive Garden.

Most North American diets are based on fats and carbs wit

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

h the majority of people getting probably half or more of all of their calories from carbohydrates. There is no wa

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

that our bodies can burn off all of these carbs so it is important to lower the amount of carbs in our diet and t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ry to raise the protein (I can deal with that in another article) a bit so that we are storing less carbs as fats.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

So this leads to the obvious question of how do we drop the carbs in our diet that can cause fat? Well there are

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a couple of ways to drop carbs. One way that I have dealt with before is by using some kind of carb blocker pill,

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

a pill to stop your body from metabolizing some of the carbs that you eat. The other way to drop the number of car

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

bohydrates in your diet is to make sure that you stop snacking and instead of having a bag of chips or a chocolate

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

bar you have a small real meal, maybe Tuna and rice or a bowl of chili. Look at different kinds of small meals an

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

d you can get to the perfect eating system of six small meals a day instead of three giant meals and a few snacks

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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