I Advice - Health and Fitness

Are you happy with the way you look? This is something we all ask ourselves from time to tim

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e, even if it's not always consciously. At some level we all think about our image every day

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

It's natural to worry about your appearance and not many of us in modern society accept tha

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

t we all age and with it grow old gracefully. In a time of plastic surgery, it appears some

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

et it right and others horribly wrong. Does Michael Jackson really look better or has he tur

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ned into an extension of his own misguided ego? On the other hand the celebrities that do lo

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

k great are the ones where you can't so obviously tell that anything dramatic has been done.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Have you heard of Botox? It's also known as Botulinum Toxin A, or rather that's what it's

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

erived from. Originally it was used to treat patients that suffered with uncontrollable blin

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

king. However, doctors treating the patients also noticed that it also improved appearance.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ot long after that, Botox became a purely cosmetic option in this regard. Botox has been use

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

for many years in doctors surgeries to treat and also prevent moderate to advanced facial w

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rinkles.

Of course, in recent years Botox has become a wonder substance on the cosmetic fro

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t to give patients a youthful appearance. The treatment is very convenient and widely regard

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ed as safe.

Areas Of Body Botox Is Used For

Botox is most commonly used to improve the app

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

arance of lines on the forehead, frown lines and what is known as 'crows feet'. Even the upp

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

er part of the lips can benefit from this treatment.

How Long Does It Last

The effects of

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

he treatment can last for several months. Only very tiny amounts of the toxin are used for c

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

osmetic procedures. It works by inhibiting the release of acetylcholine, which is a chemical

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

that triggers muscle contraction in parts of the human body and is administered by injection

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Sir Richard Branson - he started with nothing yet went on to build a whole empire under the Virgin name, now estimated to be worth over 4 billion pounds (approx 7.2 billion US dollars).

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