I Advice - Health and Fitness

Did you know that the majority of skin products including lotions, soaps, foams, butters and anti-wrinkle products just to name a few, contain synthetic ingredients t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

hat are known to damage your skin?

Have a look at the back of the bottles and you’ll see a bunch of names that I have trouble pronouncing. These products are known to contain toxins

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and cause: allergic reactions, rashes, irritation and some of these are known to cause cancer.

In this article I’ll expose 8 of these toxic ingredients to look out for:
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

g>

Methyl, Propyl, Butyl and Ethyl Paraben - These chemicals are used to extend the shelf life of products and inhibit microbial growth. These are known toxins and
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
studies show that they can be absorbed through the skin.

Diazolidinyl Urea and Imidazolidinyl Urea (urea is from urine) - These are used as preservatives. The Ameri
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

an Academy of Dermatology has found them to be a primary causeof dermatitis. These chemicals release formaldehyde (what they use to preserve dead bodies), and is highly toxic.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

g> Propylene Glycol - This has been used for a long time and used to be a vegetable glycerin mixed with grain alcohol which is natural. Today it is usually a synthetic petro

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

hemical mix. It is known to cause allergic reactions, hives and eczema. If you see PEG (poly-ethylene glycol) or PPG (polypropylene glycol) on the labels, watch out as these are rela

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ted synthetics.

Diethanolamine (DEA) and Triethanolamine (TEA) – These are often used as emulsifiers or foaming agents. They can cause allergic reactions, eye irrita

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ion and dry skin. DEA and TEA are ammonia compounds and can form cancer causing nitrosamines. They are toxic when absorbed into the body with continued use.

Petrolatum
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
g> (petroleum jelly) – This mineral oil is used for its moistening properties. It has absolutely no nutrient value for the skin and interferes with the body’s natural moisturizing pro
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a
cess leading to dryness and chapping. It gives you a quick boost where your skin feels softer and then shortly after starts to dry out your skin. Manufacturers use petrolatum because
dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod
it’s very cheap to buy.

Stearalkonium Chloride – This is an ammonium compound used in skin creams. It was developed softener and is cheaper to use than beneficial pr
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
oteins. This product is toxic and causes allergic reactions.

Synthetic Colors – You see on the bottle where it says example: FD&C Red No. 6. These colors are used to
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
make products look good and are known to be carcinogenic. Make sure you avoid using products containing these colors (and food).

Synthetic Fragrances – On many lab
t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
els you will see the word fragrance. These “fragrances” are chemicals and can contain up to 200 ingredients. Some problems caused by these chemicals are: headaches, dizziness, rashes,
ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust
violent coughing, skin irritation, vomiting, hyper-pigmentation and more.

I know it can be shocking to find out that even products for babies contain these harmful ingredients. The t
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
ruth is that these companies producing these products just want to make money and spend more money on commercials to advertise than on spending a bit more to create a quality product.
.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
If you look at the ingredients in many products labeled as “organic” you will find these same ingredients.

Conclusion

Luckily, there are some great companies out th
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip
ere that are making fantastic natural products. Once you make the switch you will immediately feel the difference. Your skin will feel soft, nourished, and you may even start to glow

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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