I Advice - Health and Fitness

Wouldn’t it be great to stop the hands of time and stay young forever? Sadly, nobody gets the privilege to enjoy eternal youth. And no matter what we do, we will all eventuall

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

y grow old. That is the unbreakable law of nature.

As we age, it is inevitable that we show some signs of the passing years. Our hair may start to thin out, lines may start s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

owing on our faces and our bodies may start to succumb to the force of gravity. Another telltale sign of growing old is the development of flat brown spots that may appear on a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

y part of the body. Oftentimes referred to as “age spots” or “liver spots”, these brown spots are actually the result of a waste build-up known in the medical community as “lip

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ofuscin accumulatio”.

Some people believe that these age spots (or liver spots) are harmless. What they do not understand is that these are actually an indication that the cel

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s of the body are slowly being poisoned by all the waste products that have accumulated over the years. These spots are actually an indication of free radical intoxication. If

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

left unchecked, this may hasten the aging process and can lead to serious health complications such as leukemia and cancer.

Thankfully, however, there are several ways to count

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

er this problem. With several lifestyle changes and with the help of some basic skin care regimen, you can deal with age spots effectively. Here are some surefire tips that ca

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

help you take care of your skin better:

•Eat your way to proper skin care. Diet plays a vital role in the development of age spots and an important consideration in any skin

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

are regimen. A diet high in fat can significantly increase free radical activity and cooking food at high temperatures (such as when frying in oil) can produce a lot of free ra

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

icals. To prevent this, adopt a high protein diet, which includes 50% raw fruits and vegetables. Also include a lot of fresh grains, seeds and nuts. Among the other food item

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s that you need to take off from your diet are caffeine, fried foods and processed foods.

•Supplement your diet and your skin care regimen with powerful antioxidants. Antioxid

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nts prevent free radical formation by pairing up with the free electrons and have the ability to detoxify the body. As such, you can get a lot of benefits by supplementing your

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

diet with these powerful antioxidants, which include vitamins (especially vitamins A, B complex, C, D and E), minerals (selenium and germanium) and enzymes (superoxide dismutase

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

and glutathione).

•Herbs for excellent skin care. For best results, use ginseng, gotu kola, licorice and sarsaparilla. They can definitely lighten those ugly spots!

•Shy aw

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

y from the sun. As every skin care specialist will tell you, the ultraviolet rays of the sun are one of the skin’s worst enemies. So, don’t forget to apply your sunblock befor

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

going out in the sun!

•Fasting and cleansing can be good for your skin. A fasting program may be necessary to eradicate age spots. It can also be a very good component of yo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ur skin care regimen. However, be sure to consult your doctor first before doing anything about it. Plus, a liver cleanse may also help fortify the action of your fast. For b

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

st results, observe three days of fasting every month and use black radish extract or dandelion root and beet juice for the liver cleanse.

•Retinoic acid to the rescue. Retino

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

c acid is being prescribed by a lot of doctors as an effective skin care treatment for a number of skin problems including age spots. Use it as directed and you cannot go wrong

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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I Advice - Skin Care - Learn How To Deal With Age Spots

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