I Advice - Health and Fitness

How many times has your wife, or your husband, or other family member nagged you about your smoking habit? No doubt you have th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ought about it, and probably agreed with them many times over, but has it actually inspired you to quit? If that answer is no,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

then you should realize by now that you can't quit because someone else tells you to, it has to be for you, on your terms and it

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

has to be sincere. Otherwise, you are probably doomed to failure.

Your loved ones might think they are helping, or encouragin

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

g you to quit, but they're actually not doing you any favors by continually going on at you to give up. Human nature dictates t

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

at by doing this, you'll naturally rebel against them, especially if they are expressing a negative or judgmental attitude towar

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ds you.

Smoking is an addiction, not just a bad habit. You can't just tell someone to quit, they have to want to. Smokers hav

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e an ingrained "defence mechanism" against almost all the important reasons for quitting. Consider how many times have you said

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

these things to yourself, or to other people who nag you to quit smoking:

* "It's my only bad habit"

* "It helps me relax a

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nd unwind after a stressful day"

* "My grandfather lived until he was 90 and he smoked 60 cigarettes a day"

* "You spend mon

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

y on - insert your own reason here - so it's the same amount as the cost of my cigarettes"

Do you recognise these tactics? Smo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

kers use them all to time to justify their habit to themselves, and in their minds, to those who are questioning them about why

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

they don't want to quit. Your spouse or partner can say it as many times as they like, but you'll always find an answer - that

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

is unless you really want to quit!

So, how can you take that all-important step towards quitting smoking for YOU? First of all

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

, you need to re-train your brain to get rid of all of these ill-conceived excuses. Find a good reason for you to quit, for you

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

rself and not for others. It doesn't matter what your reason is, as long as you believe it. It could be money orientated, mayb

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

you want to save up for that expensive car you've always dreamed about, or you'd love to go on an extended vacation. Health, o

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

f course, is a big issue too. If you've been feeling a bit breathless lately, or an annoying cough won't go away, it could be t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ime to stop and consider how quitting smoking would relieve this.

Whatever your personal motivation is, the important thing is

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

to find it, and to start planning your "quit smoking day" - not for your wife, nor your husband, partner or friend - but for you

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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