I Advice - Health and Fitness

More than 44 million people in the U.S. smoke cigarettes every day. If you're one of them, and you've already tried to quit at least once, then you know what a bear breaking a nicotine addiction is. But you also know how important it is f

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

or your health.

I’m sure you’ve read and heard every bad thing about what smoking does to your health…but as a doctor I wouldn’t feel helpful if I didn’t remind you again. As doctors, all we can hope for is that somewhere along the line…

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

omething clicks.

Most of my patients think that smoking is only related to lung disease. But that’s just the “tip of the iceberg”. Cigarette and cigar smoking can also damage your arteries, dramatically increasing your risk of heart dise

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ase.

Chemicals in cigarettes can cause inflammatory responses all over your body. Inflammation can then trigger a reaction in the artery walls that eventually leads to a harder, less flexible wall and plaque build-ups.

To make matters w

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rse, cigarettes also increase your levels of fibrinogen, a clotting agent that increases your heart attack risk.

These same factors that put you at risk for heart disease and heart attack also increase your risk of a stroke. The arteries

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

that carry blood to your brain can become hardened. If a clot forms in one of these arteries, it can block off blood to your brain, causing damage, paralysis, or even death.

Now here’s something else you probably never considered. Smokin

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

g also affects other cancers like bladder cancer and colon cancer. And it can also make it harder for you to overcome cancer. For example, men who smoke don’t respond as well to prostate cancer treatments.

And then there are the affects

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

hat smoking has on your physical appearance. Your teeth turn yellow, your breath is bad, and your skin becomes leathery and rough.

There's no doubt that the reasons to quit smoking are nearly endless. If only it were that easy…

When it

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Comes to Quitting Keep Trying Until You Get it Right!

I once heard a patient who had successfully quit smoking say it only took 90 seconds. I was puzzled. She told me she'd tried to quit several times, but every time she found herself sm

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

king again.

One day, when she wanted a cigarette, she realized she was out and had forgotten to buy her next pack. On her way to the store, she noticed the craving had passed. When the next craving struck, she timed it. It lasted 90 seco

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ds.

From there, she realized if she could resist every intense craving for just 90 seconds she'd be all right. This change in thinking worked for her, but it took her several tries to come up with the right way for her to quit smoking.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

It's up to you to keep trying new methods until you find the right way for you to quit smoking. Here are some suggestions:

Find Support: For some people, a support group is key. It helps to be around people who are in the same place as y

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

u, trying hard to quit. And it helps to be around people who have successfully quit. Support does make a difference. According to the Mayo Clinic, people who seek support when they quit are more likely to remain cigarette-free.

Hypnother

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

apy: If you're ready to quit smoking and committed to following through, then hypnotherapy might prove helpful. It doesn't work for everyone, but for some people it makes the difference. Remember, this is about trying different strategies

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

until you find the one that helps you quit successfully.

Nicotine replacement: Both nicotine gum and the nicotine patch can help you satisfy your nicotine cravings without lighting up. You can use them to slowly wean yourself of the addi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tion rather than quitting cold turkey, which can be exceptionally difficult.

Herbal assistance: There are many herbal smoking cessation programs available online or through your local health food store. For some people, these herbal reme

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

dies really work. You won't know unless you try. I recommend that you choose one that is guaranteed or you get your money back. That way you know the company stands behind its product, and you won't be out a bunch of cash if you still wak

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

up with unbeatable cigarette cravings each morning.

Prescriptions: While prescriptions always carry the risk of side effects, if no other method of quitting is working for you, then a prescription for Zyban might be worth considering. Z

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

yban works to balance the chemicals in your brain thought to be responsible for smoking cravings. It's not the first option I recommend, but when you've tried several things with no luck, it might be time for a medical solution.

The key

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

o success when it comes to quitting is to not give up until you find a strategy that works for you. There's no easy way out when it comes to smoking, but you do have options and success is possible… you just have to keep at it.

Stay well

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.iadvice.org.ua/article/262921/iadvice-Does-Nicotine-Have-A-Hold-On-You-Today-Might-Just-Be-A-Day-To-Quit--And-Save-Another-Life--Yours.html">Does Nicotine Have A Hold On You? Today Might Just Be A Day To Quit - And Save Another Life - Yours</a>

BB link (for phorums):
[url=http://www.iadvice.org.ua/article/262921/iadvice-Does-Nicotine-Have-A-Hold-On-You-Today-Might-Just-Be-A-Day-To-Quit--And-Save-Another-Life--Yours.html]Does Nicotine Have A Hold On You? Today Might Just Be A Day To Quit - And Save Another Life - Yours[/url]

Are you really doubtful about what would be the best work at home job that would fulfill your needs? With most people, before they even think about the whole project, they ask themselves this one question.

Homeowner loan is of secured type of loan where presence of collateral security is necessary. Specially meant to homeowners, this loan is easy to avail. Along with, availing it lets you have advantages like low interest rate, loner repayment period, and higher loan amount

We all understand the importance of health insurance; however, as the types of health insurance continue to increase it is becoming more and more difficult to select the type of coverage that is best for you and your family.

Tags

Links

I Advice - Does Nicotine Have A Hold On You? Today Might Just Be A Day To Quit - And Save Another Life - Yours

Related Articles: