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    · 390,000 American people die from the effects of smoking each year.
    · Men are 22 times more likely to develop lung cancer by smoking
    · Women are 12 times more likely.
    · It c
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ost a lot of money
    · It is unsociable
    · You stink and so does you house and clothes

    Just to show you that I know what I am talking about: I used to smoke 60 a day and stopped just
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ike that. I did it…you can do it. I am not saying that it is easy, but it can be done and you will feel much better for it. Make a list of reasons why you want to stop smoking. This will mea
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    n very different things to different people, but if you know what you want from stopping, it could help you through the most difficult moments. A very important part of this is to know what
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ou would gain and what you would lose from stopping smoking.

    To stop smoking need not cost you any money. Do it my way and believe me it will change you life. First let us diverse a bit and
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    talk about your mind.

    Your mind is made up of two parts
    · -the conscious, This is the part of your mind that makes judgments, comparisons it is the awake bit of you, the part you a
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    re using to read this,
    · and the unconscious or subconscious which is best illustrated as a three year old genie.

    Your subconscious mind is a very resourceful and efficient tool.
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    The subconscious can not determine right from wrong
    · It does not judge.
    · The more precise you want the outcome, the more efficient the subconscious mind can become.

    Just imag
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ne saying to a three year old child the way to boil an egg - "Stand in boiling water for three minutes". The unfortunate child would try to get his feet in the pan.

    You have to be very preci
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    se with such directions because a three year old doesn't think – he/she accepts.

    In exactly the same way your subconscious mind doesn't think. It's thinking is the job of the conscious mi
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    d. Thinking is a conscious activity. The subconscious mind just accepts and does. So it needs clear and explicit instructions. No maybes, its, or buts.

    So what does it do this subconscious m
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    nd? Just what it is told to do and you do that in as clear a manner as possible.

    I hope you are getting the picture as to how this will stop you smoking. So read on there is a bit more yet.
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    There are rules to this “ telling your subconscious “ what to do. I will keep this very simple for the sake of this article ( in this field there is a whole book ) after all , what you want
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    o do is Stop Smoking.

    The Rules:
    · Be precise
    · Must be positive. Through study it is know that the subconscious mind only accepts positive commands, not negative equivalents. If t
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ere is something you want to be rid of, phase it positively. You must leave out words like “give up” “not” “never”
    · Write down exactly what you want. Part of the reason why we write do
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    wn our commands is to create a set of instructions for our subconscious mind to carry out.
    · Must be written in the first person “I”…I have…I am
    · The command must be read at leas
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    twice a day. Preferably rewritten
    · After each reading visualize you life with the command achieved.
    · Do not tell anyone about what you are doing. They will ridicule you and give
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    our reasons why it will not work. This will pull you down.

    Do not “Give up smoking” But “ I live a health lifestyle and see myself as a healthy person”

    These techniques are used by all sort
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    s of people for all sorts of reasons. People who are achievers. Do not simply scribble something down on a piece of paper and hope it will work.

    You have two choices:

    · Put your whole commi
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ment behind it and get in the right frame of mind to face the challenge.
    · Continue as you are and become one of the 390,000 American people who die from the effects of smoking each year


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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